Basal Metabolism in Health and Disease

"Basal Metabolism in Health and Disease" is a seminal scientific treatise that explores the fundamental principles of human metabolism and its clinical applications. Written by Eugene F. Du Bois, a pioneer in the field of physiological chemistry, this work provides an exhaustive examination of the energy requirements of the body at rest and the various factors that influence these rates in both healthy individuals and those suffering from diverse medical conditions.

The text delves into the methodology of measuring metabolic rates, offering detailed insights into the instrumentation and experimental techniques of the early twentieth century. It covers the metabolic implications of endocrine disorders, particularly those affecting the thyroid gland, as well as the effects of age, sex, and environmental factors on energy expenditure. By synthesizing clinical observations with laboratory data, the book serves as a cornerstone for the study of nutrition, endocrinology, and internal medicine.

This comprehensive study remains a vital reference for understanding the historical development of metabolic science. It highlights the transition from theoretical physiology to practical diagnostic medicine, emphasizing the importance of precise measurement in the treatment of disease. "Basal Metabolism in Health and Disease" is an essential resource for medical historians, physiologists, and practitioners interested in the evolution of metabolic research and its enduring impact on healthcare.

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