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Computing for Comparative Microbial Genomics

Name: Computing for Comparative Microbial Genomics
Brand: Springer London Ltd
SKU: 01433904
Price: 47.35 EUR
Availability: InStock
Author: David W. Ussery
ISBN: 9781848002548

Bioinformatics for Microbiologists

David W. Ussery

Trudy M. Wassenaar

Stefano Borini

Language

English

Book Hardback

Libristo code: 01433904

Publishers Springer London Ltd, December 2008

The problem many microbiologists face is simply that of too much information. This book details many... Full description

Libristo code: 01433904

115 b

47.35 €

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The problem many microbiologists face is simply that of too much information. This book details many published methods for comparison of genomes, and provides examples of how custom comparisons can be made. The choice of methods obviously depends on the questions to be asked, and of course on the quantity of genomes to be compared. Two similar bacterial chromosomes can simply be aligned with each other, and regions of inversions and deletions can be readily visualised. However, this method won t work to compare hundreds of genomes, where 2-Dimensional clustering heat maps would be useful.§§This text is built around teaching COMPUTATIONAL / BIOINFORMATIC methods for comparison of microbial genomes, and includes detailed examples of how to compare them at the level of DNA, RNA, and protein, in terms of structural / functional analysis.§§Aimed at advanced undergraduate and graduate students in Bioinformatics and Microbiology, this book will prove an invaluable reference to computational and bioinformatics tools.