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Appropriate Dose Selection - How to Optimize Clinical Drug Development

Jezik EngleskiEngleski
Knjiga Tvrdi uvez
Knjiga Appropriate Dose Selection - How to Optimize Clinical Drug Development Jürgen Venitz
Libristo kod: 01560893
Nakladnici Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, listopad 2006
Optimal dose individualization has become more important in improving clinical efficacy and safety,... Cijeli opis
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Optimal dose individualization has become more important in improving clinical efficacy and safety, given the variability in drug response, e.g., due to concurrent illnesses or co-medications. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. The continued use of biomarkers based on the (known) pharmacology of the drug and/or biology of the underlying disease along with exposure response evaluation throughout all phases of drug development can quantitatively integrate clinical pharmacology knowledge, provide early proof of concept, and help in rational dose selection and rational drug product labeling for clinical use.

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Informacije o knjizi

Puni naziv Appropriate Dose Selection - How to Optimize Clinical Drug Development
Autor Jürgen Venitz, Wolf Sittner
Jezik Engleski
Uvez Knjiga - Tvrdi uvez
Datum izdanja 2006
Broj stranica 216
EAN 9783540278672
ISBN 3540278672
Libristo kod 01560893
Nakladnici Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Težina 477
Dimenzije 149 x 211 x 20

Kategorija

Medicine & Nursing > Medicine: general issues > Medical equipment & techniques > Medical research
Medicine & Nursing > Clinical & internal medicine > Diseases & disorders > Oncology
Technology, Engineering, Agriculture > Industrial chemistry & manufacturing technologies > Industrial chemistry & chemical engineering > Pharmaceutical chemistry & technology
Medicine & Nursing > Medical specialties, branches of medicine > Pharmacology
Mathematics & Science > Biology, life sciences > Biochemistry
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