Kontakt
Kako kupovati
Dostava
Savjetnik za kupnju
Asymmetric Transfer Hydrogenation with Immobilized Catalysts
Reusable catalysts for the production of chiral compounds
Engleski
116 b
30 dana za povrat kupljenih proizvoda
Kupci su kupili i
/
Meki uvez
111.49
€
To meet the increasing demand for single enantiomers (e.g., for the production of pharmaceuticals) efficient manufacturing techniques are required. This thesis is concerned with the immobilization of transition metal catalysts that can be used for the asymmetric transfer hydrogenation of prochiral ketones. The aim was to improve the overall efficiency of this method by facilitating separation and reuse of the catalysts. This was achieved via heterogenization of a rhodium complex using surface-functionalized polymers as supports. A systematic study of the catalytic system was conducted to determine the optimal reaction conditions and kinetics. High activity, enantioselectivity, and reusability are achieved using an aqueous solution of sodium formate/formic acid as hydrogen source and reaction medium. Simple separation and high robustness of the catalysts further indicate potential for application in the industrial production of enantiomerically pure compounds.
Informacije o knjizi
Engleski
Kategorija
