Cancer Stem Cells and Signaling Pathways

Despite recent advances in tumor therapy and a greater understanding of their biology, tumors continue to be a prevalent and fatal disease worldwide. According to a novel paradigm in tumor biology, a small percentage of the cells within a tumor known as cancer stem cells (CSCs) are predicted as a crucial population for tumor progression. Cancer Stem Cells and Signaling Pathways explores the mechanism of cancer stem cell signaling pathways in cancer advancement. It also serves as an ideal reference to guide investigators toward further valuable answers to problems associated with anti-cancer treatments and an understanding of the crosstalk among the signaling pathways in CSC regulation. Presents cancer stem characteristics and their signaling pathways Highlights use of animal models for cancer research, the use of genetically modified stem cells to deliver antitumor agents, and the significance of stem cell signaling in drug discovery Covers basic and translational research appropriate for scientists and clinicians exploring alternative treatments for various cancers from multi