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Cell Cycle Control and Dysregulation Protocols

Jezik EngleskiEngleski
Knjiga Tvrdi uvez
Knjiga Cell Cycle Control and Dysregulation Protocols Antonio Giordano
Libristo kod: 01400916
Nakladnici Humana Press Inc., srpanj 2004
The dysregulation of the normal cell cycle underlies an enormous number of pathological conditions,... Cijeli opis
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The dysregulation of the normal cell cycle underlies an enormous number of pathological conditions, including the neurodegenerative disorders, all cancers, and diabetes. In Cell Cycle Control and Dysregulation Protocols: Cyclins, Cyclin-Dependent Kinases, and Other Factors, expert laboratorians detail emerging methodologies for studying the cell cycle, its kinases, and kinase inhibitors. The authors focus on issues of gene expression in vivo and in vitro, the analysis of cyclin-dependent kinase inhibitors, protein degradation mediated by the proteosome, the analysis of the transformed cell phenotype, and innovative techniques to detect apoptosis. Many of the protocols are new, such as electron microsocopy to detect apoptosis and proteosome-mediated degradation, whereas others study the interactions between protein-protein, protein-DNA, and protein-RNA. The protocols follow the successful Methods in Molecular Biology series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.§State-of-the-art and highly practical, Cell Cycle Control and Dysregulation Protocols: Cyclins, Cyclin-Dependent Kinases, and Other Factors offers pathbreaking researchers powerful tools for probing the cell cycle regulation across a wide variety of pathologies.

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Informacije o knjizi

Puni naziv Cell Cycle Control and Dysregulation Protocols
Jezik Engleski
Uvez Knjiga - Tvrdi uvez
Datum izdanja 2004
Broj stranica 185
EAN 9780896039490
ISBN 0896039498
Libristo kod 01400916
Nakladnici Humana Press Inc.
Težina 508
Dimenzije 155 x 235 x 17
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