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The book layout consists of three sections in eleven chapters. Section one; Mucosal immunology in healthy human beings, it covers the mucosal immunology of ear, nose, throat and oral cavity as well as the mucosal immunology of neck and head. Section two, Mucosal immunology in disease state, it presents the mucosal cryoglobulin, mucosal immune profiling of urinary tract infections, mucosal immunology of human bacterial infectious diseases in Babylon area/IRAQ .The third section states the vaccine disease prevention and devoted to mucosal vaccines as it is related to systemic vaccines. This text is intended to be of use for immunology students and researchers.