Industrial Process Scale-up

Industrial Product and Process Scale-up: A Practical Innovation Guide from Idea to Commercial Implementation, Third Edition serves as a comprehensive guide for all aspects of process and product scale-up from idea generation, through R&D, engineering, procurement, construction to implementation, providing insights on identifying and mitigating risks associated with commercial scale implementation - providing insights on identifying and mitigating risks associated with commercial scale implementation. The Third Edition introduces new strategies for product scale-up and integrating product and process scale-up across six innovation stages, offering methods for pilot plant decision-making, scale-down processes, and evaluation criteria for demo-plant versus commercial scale plant selection. Special emphasis is placed on unit operation scale-up methods and intensified process steps to aid decision-making during the feasibility stage, benefiting industries like pharma and active pharma ingredients. This book will be a valuable guide to researchers in industry, working to scale-up products and processes across commercial sectors. This book will also be a very useful guide to late-stage students and academics working in industrial chemical process engineering.

• Describes successful and failed industrial cases and their analysis, including real-world examples
• Offers easily accessible, step-by-step and concise guidelines for industrial process scale-up
• Based on industrial experiences and practices that reduce the risks of commercial scale implementation of new processes to acceptable levels and reduce cost and time of process innovation
• Explains each stage of the innovation funnel, from research, development, demonstration and commercial implementation for any process type and branch
• Provides heuristics to decide for a down-scaled pilot plant
• Offers complete methodology for six unit operations scale-up methods to select from, including case studies