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Omeprazole
A comparative in vitro dissolution study of different brands of omeprazole magnesium with reference product Losec 20
Engleski
106 b
30 dana za povrat kupljenih proizvoda
Moglo bi vas zanimati i
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Meki uvez
75.83
€
/
Meki uvez
47.38
€
/
Tvrdi uvez
26.52
€
The main objective of present investigation was to study the dissolution pattern of most commercially available formulations of omeprazole in Bangladesh . Omeprazole magnesium is the most common antiulcerant in Bangladesh which are widely prescribed by the physicians for peptic ulcer & GERD. Ten national brands with reference brand of Omeprazole magnesium capsules were studied in stimulated gastric medium (pH 1.2) for first 2 hours and then in simulated intestinal medium (pH 6.8) for next 45 minutes using USP reference dissolution apparatus (Type 1 ) Among most of these locally manufactured Omeprazole brands showed compatible dissolution pattern & release kinetics compared with the reference brand. It was concluded from the study that most of the formulations were equivalent and there was no intra and inter variation between each and every formulation.
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Engleski
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