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Statistical Methods for CGH Array Analysis

Jezik EngleskiEngleski
Knjiga Meki uvez
Knjiga Statistical Methods for CGH Array Analysis Pei Wang
Libristo kod: 06820282
Nakladnici VDM Verlag, veljača 2010
Genomic DNA copy number alterations are key genetic events in the initiation and progression of huma... Cijeli opis
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Genomic DNA copy number alterations are key genetic events in the initiation and progression of human cancers. Recent advance in the technique of microarray comparative genomic hybridization (array CGH) enables one to screen genome-wide for all possible regions with DNA copy number alterations, such as chromosome gains and losses, or localized amplifications and deletions. In this book, we introduce two statistical methods addressing two different questions for the data analysis of array CGH. The first method---Cluster Along Chromosomes--- is developed for calling gains and losses in CGH arrays. The second method--- Boosted PRIM (Patient Rule Induction Method)--- is developed to search for oncogenic pathways using array-CGH data. The performance of the methods are illustrated through both simulation studies and real applications.

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Informacije o knjizi

Puni naziv Statistical Methods for CGH Array Analysis
Autor Pei Wang
Jezik Engleski
Uvez Knjiga - Meki uvez
Datum izdanja 2010
Broj stranica 38
EAN 9783639114065
ISBN 363911406X
Libristo kod 06820282
Nakladnici VDM Verlag
Težina 68
Dimenzije 152 x 229 x 2

Kategorija

Mathematics & Science > Mathematics > Probability & statistics
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