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Structural Alignment

A Graph-Theoretic Approach

Jezik EngleskiEngleski
Knjiga Meki uvez
Knjiga Structural Alignment Layal Kazma
Libristo kod: 06835132
Nakladnici VDM Verlag, ožujak 2011
Structural alignment is the process of finding similarities between a pair of proteins based on thei... Cijeli opis
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Structural alignment is the process of finding similarities between a pair of proteins based on their three-dimensional shape. Accurate detection of such similarities could reveal evolutionary relationships and predict the functions of different proteins. Despite the existing algorithms, the protein structure alignment problem is not completely solved. In this work a graph-theoretic approach is considered, which consists of representing tertiary protein structures as labeled graphs, and interpreting the structural alignment problem as a particular case of the Maximum Common Subgraph (MCS) problem. Our algorithm was then implemented under parallel platforms using a combination of threads and message passing techniques. Experiments were performed on a set of proteins selected randomly from the Protein Data Bank. The experiments proved the time- efficiency and accuracy of our method when compared to several other algorithms.

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Informacije o knjizi

Puni naziv Structural Alignment
Autor Layal Kazma
Jezik Engleski
Uvez Knjiga - Meki uvez
Datum izdanja 2011
Broj stranica 80
EAN 9783639279368
ISBN 3639279360
Libristo kod 06835132
Nakladnici VDM Verlag
Težina 127
Dimenzije 152 x 229 x 5
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