Synthesis of Five-Membered Heterocycles

Over the years, heterocyclic compounds, especially five-membered, have drawn more attention of pharmaceutical community because of their therapeutic value. The formation of heterocyclic compounds has turn out to be the keystone of synthetic organic chemistry. Dimethylformamide has played an important role in organic synthesis for a long time and it is frequently utilized as a common solvent for chemical reactions and broadly used in industry as a reagent. It is a unique chemical, being an efficient polar aprotic solvent, it can play three other roles in organic chemistry i.e. as stabilizer, reagent, and catalyst. Due to its structure, DMF can participate in several reactions as a versatile building block for several units. With Synthesis of Five-Membered Heterocycles: Role of DMF as Solvent, Reagent, Catalyst, and Stabilizer, readers will be able to quickly assess possible synthetic approaches. The audience – researchers, academic professionals, and synthetic chemists both in industry and academia – will have detailed information about the synthesis of five-membered heterocyclic compounds using dimethylformamide. Includes comprehensive description of heterocycle synthesis Highlights many methods for the synthesis of five-membered heterocyclic compounds using dimethylformamide