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A protein with no genes of its own can infect a brain - and no one saw it coming.
Prions are infectious agents made entirely of misfolded protein - no DNA, no RNA - a finding that forced scientists to rewrite assumptions at the core of molecular biology, from a remote epidemic to a cattle crisis that reshaped food safety worldwide.
Modern structural biology has exposed the shape-based mechanism behind infection, along with unsettling evidence linking related processes to Alzheimer's and Parkinson's - raising stakes far beyond one rare, incurable disease.
Inside, you'll discover:
- How a protein with no genes learned to copy itself
- Why a cattle epidemic became a global public health crisis
- The unsettled debate linking prions to Alzheimer's and Parkinson's
Part of the What Science Says About... series, evidence-based explorations of science's most compelling mysteries.
Step into the science - and see what's actually proven.
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